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In an effort to discover the source of the epidemic, House begins treating the children.
However, when the kidneys of two of the children shut down, House is forced to test which drug caused the failure, resulting in one of the babies dying.
But then Brandon's white blood cell count drops, proving both doctors wrong.
At the clinic pharmacy, House theorizes that Brandon was accidentally given colchicine instead of cough medicine, which explains all of his symptoms aside from his cough.
Using an experimental anti-virus, they successfully cure the remaining babies.
House, determined to find the entry point of the virus, finds an elderly hospital volunteer coughing and wiping her nose as she pushes around a cart of baby toys and blankets and makes the connection.
Following an autopsy, the team discovers the presence of Echovirus 11, CMV, and Parvovirus B19 antibodies.
They test the mothers and decide the cause of the epidemic is the Echovirus.
Seeing House and his team as a waste of time and resources, he decreases their salaries, eventually forcing House to fire one of his team members.House confirms his diagnosis with a retinal biopsy and successfully cures Dan.A college student named Brandon (Kevin Zegers) collapses after having sex with his fiancée.Sister Augustine (Elizabeth Mitchell), a nun, arrives at the hospital with her hands covered in rash, but House quickly dismisses the case after treating with antihistamines, suspecting an allergic reaction, to dish soap.However, she has an asthma attack and House administers epinephrine, causing her heartbeat to increase.